One function of thyroid hormones is to control energy availability and expenditure. Some individuals have mutations in their thyroid hormone receptor-beta (THRB) gene and are resistant to the effects of thyroid hormones. This causes their levels of circulating thyroid hormones to become elevated, but the effects of this have not been completely determined. However, researchers now determined that adults and children with THRB mutations have markedly increased resting energy expenditure.
Metabolism: Understanding Resistance To Thyroid Hormones
March 14th, 2010 by Newspublichealth.com
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