Archive for September, 2009

Key Mechanism In Development Of Nerve Cells Found

Chaos brews in the brains of newborns: the nerve cells are still bound only loosely to each other. Researchers have been studying how a neural network capable of processing information effectively is created out of chaos. A team in Finland has now found a new kind of mechanism that adjusts the functional development of nerve cell contacts.

Young Adults May Outgrow Bipolar Disorder

Bipolar disorder, or manic-depression, causes severe and unusual shifts in mood and energy, affecting a person’s ability to perform everyday tasks. With symptoms often starting in early adulthood, bipolar disorder has been thought of traditionally as a lifelong disorder. Now, researchers have found evidence that nearly half of those diagnosed between the ages of 18 and 25 may outgrow the disorder by the time they reach 30.

Natural Compound In Extra-virgin Olive Oil — Oleocanthal — May Help Prevent, Treat Alzheimer’s

Oleocanthal, a naturally-occurring compound in extra-virgin olive oil, alters the structure and increases antibody recognition of neurotoxic proteins associated with Alzheimer’s disease. The structural change impedes the proteins’ ability to damage brain nerve cells, while increased antibody recognition may enhance immunotherapy-based treatments. The findings suggest that oleocanthal may have potential as a preventative and therapeutic agent for Alzheimer’s.

New Chemically-activated Antigen Could Expedite Development Of HIV Vaccine

Scientists working to develop a vaccine for the human immunodeficiency virus report they have created the first antigen that induces protective antibodies capable of blocking infection of human cells by genetically-diverse strains of HIV. The new antigen differs from previously-tested vaccines by virtue of its chemically-activated property that enables close sharing of electrons and produces strong covalent bonding. Researchers used a mouse model to generate the antibodies.

New Target To Prevent Fatal Flu Lung Complication Identified

New research has identified a therapeutic target for acute lung injury resulting in acute respiratory distress syndrome, a highly fatal complication of influenza infection.

Nutraceutix receives Chinese patent for probiotic and nutraceutical delivery technology

The Chinese Patent Office has issued Nutraceutix, Inc. patent No. 02823678.5 for BIO-tract. It is the fourth international patent, from many patents pending, that the technology has been awarded recently based on BIO-tract’s ability to protect sensitive ingredients such as probiotic organisms from stomach acid on their way to optimal release sites in the intestinal tract.

U.S. patent for Idaho’s high resolution nucleic acid melting techniques

Idaho Technology’s patent portfolio continues to grow as the U.S. Patent and Trademark Office granted the company U.S. Patent No. 7,582,429 relating to methods of performing genetic analysis in the presence of a double-stranded nucleic acid binding dye.

Cordis Corporation, Boston Scientific enter agreement to resolve Palmaz infringement suit

Cordis Corporation (“Cordis”) announced today that it has reached an agreement with Boston Scientific (“Boston”) resolving its Palmaz infringement suit relating to Boston’s NIR stent, settling several other cardiology-related cases relating to patents in the Ding, Kastenhofer, Palmaz, and Fontirroche patent families, and exchanging paid-up licenses for certain intellectual properties.

Altered state physiology drug development platform to treat an array of human conditions

David H. Fater, CEO of Vicor Technologies, Inc., today announced that on July 23, 2009, the Australian Patent Office issued it a Deed of Letters Patent for its altered state physiology drug development platform. Vicor Technologies is a biotechnology company focused on the commercialization of innovative, non-invasive medical devices and diagnostics using its patented, proprietary PD2i® nonlinear algorithm and software to stratify patients at risk of sudden cardiac death and trauma victims in need of lifesaving intervention.

IP Advocate founder to speak on commercialization barriers faced by university faculty inventors

Speaking of the then-divided Berlin, former President Reagan famously admonished Soviet leader Gorbachev to “tear down this wall.” In a similar spirit, IP Advocate founder Dr. Renee Kaswan is calling on the university technology transfer system to remove the barriers that keep innovations from moving swiftly into the marketplace.

U.S. PTO to reexamine the patents in Cellectis-Precision BioSciences litigation

Precision BioSciences, Inc. today announced that the United States Patent and Trademark Office (PTO) has granted Precision’s requests for inter partes reexamination of U.S. Patent Nos. 6,610,545 (the ‘545 patent) and 7,309,605 (the ‘605 patent), which Cellectis SA (Alternext: ALCLS) has asserted against Precision in litigation.

PolyMedix receives patent protection for computational methods in the design of amphiphilic polymers

PolyMedix, Inc., an emerging biotechnology company developing new therapeutic drug products to treat infectious diseases and acute cardiovascular disorders based on biomimetics, has received patent protection for certain exclusively licensed intellectual property by the issuance to the University of Pennsylvania of U.S. patent number 7,590,517, “Methods, Systems, and Computer Program Products for Computational Design of Amphiphilic Polymers.”

Illumina to defend Genome Analyzer System patent infringement suit

Illumina, Inc. today announced that it has been served with a complaint filed on September 21, 2009 in the U.S. District Court in Wilmington, Delaware naming Illumina as a defendant. The complaint names as plaintiffs Life Technologies Corporation; Applied Biosystems LLC; a Russian research institute; two individuals listed as inventors on the asserted patents; and another individual who appears to have an ownership interest in the patents.

Ban, Clinton Call For Increased Food Security Efforts

At a meeting on Saturday of “leaders, ministers, experts and non-governmental organizations from nearly 100 countries,” U.N. Secretary-General Ban Ki-moon called for greater urgency in the fight against hunger, Agence France-Presse reports. According to Ban, 2009 has seen an increase in malnutrition rates around the world (9/26).

Secretary Of State Clinton Announces Food Security Initiative

Secretary of State Hillary Rodham Clinton on Friday “unveiled … a food security initiative launched by the Obama administration to combat hunger worldwide,” the Associated Press reports.

Children Of Working Mothers Are More Likely To Lead Unhealthier Lifestyles

Research published ahead of print in the Journal of Epidemiology and Community Health reports that children of working mothers are likely to lead unhealthier lifestyles than those whose mothers do not work. The study suggests they are more sedentary and are more likely to be driven to school. The research was based on more than 12,500 five year old singleton children who were part of the UK Millennium Cohort Study.

New American Cancer Society Cookbook Offers 100 Nutritious Recipes To Help Cancer Patients Get Well During Treatment

Cancer patients have unique nutritional needs, and a person’s appetite may change daily based on the type of treatment they are receiving. Although nutrition is critical to getting well from cancer, eating is often one of the hardest things cancer patients have to face due to treatment side effects such as nausea, vomiting, diarrhea, constipation, mouth sores, swallowing problems, and unexpected weight loss.

Findings Of ISU Study: Intervention Program Helps Kids Eat Healthier, Reduce Screen Time

A new Iowa State University study found that a family, school and community intervention program helps children live healthier lives and could be a new tool in the fight against the nation’s childhood obesity epidemic.

Study Underway On Whether Aspartame Affects Sensitive People

Aspartame is 150 times sweeter than sugar and is found in thousands of products, including sodas (fizzy drinks), yogurts, chewing gum, cereal bars and diet foods. The University of Hull, England, has been commissioned by The Food Standards Agency (FSA), UK, to assess whether aspartame causes symptoms in individuals who feel they are sensitive to it. Competent British and European agencies say that aspartame is safe to consume.

Social Background Weighs Heavily On Teenage Diet

Teenagers’ attitudes to diet and weight are shaped by their social class, according to new research funded by the Economic and Social Research Council. Policymakers have long insisted on the importance of understanding young people’s health and eating habits but this is the first study to show how everyday practices and perceptions of different social classes contribute to variation in the diet, weight and health of teenagers.

MSU Scientist Helps Map Potato Genome; Move Will Improve Crop Yield

It’s been cultivated for at least 7,000 years and spread from South America to grow on every continent except Antarctica. Now the humble potato has had its genome sequenced. “The potato is the most important vegetable worldwide,” said Robin Buell, an MSU associate professor of plant biology. She was part of the consortium that released the first draft sequence of the potato genome.

Association Betgween Vitamin D Deficiency In Younger Women And Increased Risk Of High Blood Pressure In Mid-Life

Vitamin D deficiency in premenopausal women may increase the risk of developing systolic hypertension 15 years later, according to research reported at the American Heart Association’s 63rd High Blood Pressure Research Conference. Researchers examined women enrolled in the Michigan Bone Health and Metabolism Study and analyzed data from 559 Caucasian women living in Tecumseh, Mich.

Nurses Applaud Ageing Minister’s Tough Stand, Australia

Ged Kearney, Federal Secretary of the Australian Nursing Federation (ANF) today congratulated the Federal Minister for Ageing, Justine Elliot for sanctioning the Radford Private Nursing Home in Reservoir, Victoria. Ms Kearney said the Federal Governments’ tough stance would ensure aged care facilities understood they faced real consequences if they didn’t meet minimum standards.

Private Health System Takes Root In British Columbia

The Los Angeles Times reports that consumers in Canada are “beginning to flirt with private-sector medicine.” “Hoping to capitalize on patients who might otherwise go to the U.S. for speedier care, a network of technically illegal private clinics and surgical centers has sprung up in British Columbia, echoing a trend in Quebec.

Senate Finance Committee Weighs Minimum Benefits Under Health Reform; Public Option Amendment Expected

At Friday’s Senate Finance Committee markup of its health reform, the committee voted 14-9 to reject an amendment by Senate Minority Whip Jon Kyl (R-Ariz.) that would have eliminated a proposal in the bill to allow the federal government to determine a minimum set of health benefits that insurers must provide. Kyl defended his amendment, saying that such regulations would raise the cost of insurance. Sen. Debbie Stabenow (D-Mich.

AAP Policy: Learn About School Nursing Services

Many children who take medications need them during the school day. In a revised policy statement, “Guidance for the Administration of Medication in School,” the AAP issues recommendations for school districts, pediatricians and other child health professionals. The AAP recommends that pediatricians prescribe medications for administration at school only when necessary.

Scholarships Funded Through Robert Wood Johnson Foundation New Careers In Nursing Program

Loyola University Chicago Marcella Niehoff School of Nursing (MNSON) has been awarded Robert Wood Johnson Foundation (RWJF) funding through the RWJF New Careers in Nursing Scholarship Program. Grants provided through this program will be used for scholarships to maximize diversity and increase the quantity of students enrolled in MNSON’s Accelerated Bachelor of Science in Nursing (ABSN) program.

Two Nurses Awarded Lundbeck Neonatal Nursing Career Path Scholarships

The National Association of Neonatal Nurses (NANN) is proud to announce the recipients of the Lundbeck Neonatal Nursing Career Path Scholarship. The program, made possible through a grant from Lundbeck Inc. (formerly Ovation Pharmaceuticals), supports clinical neonatal nurses who seek to advance their education and become neonatal nurse practitioners. Recipients Motria A. Lonchyna, BSN, RN of Children’s National Medical Center in Washington, D.C., and Taryn M.

March Of Dimes Supports Screening, Education And Intervention Tools To Prevent Preterm Birth

A gathering of the nation’s leading maternal-child and quality assurance health care experts will review and develop programs that may help lower the nation’s costly preterm birth rate. The symposium, which will be held Oct.

Training By Experience For Medical Students Involved In Nursing Home Program

A geriatric training method pioneered by Marilyn R. Gugliucci, PhD, president of the Association for Gerontology in Higher Education (the educational branch of The Gerontological Society of America) has proved successful enough that she plans to implement it on a national level. This project, called Learning by Living, involves students residing in a nursing home for two weeks to better understand the experience of aging in a long-term care setting.

ALS Stem Cell Trial Gets FDA Go Ahead

The US Food and Drug Administration (FDA) said the first clinical trial to test a new stem cell treatment for the fatal neurodegenerative disease ALS (amyotrophic lateral sclerosis) this month (ALS) can go ahead.

Study Identifies Two Chemicals That Could Lead To New Drugs For Genetic Disorders

UCLA scientists have identified two chemicals that convince cells to ignore premature signals to stop producing important proteins. Published in the Sept. 28 edition of The Journal of Experimental Medicine, the findings could lead to new medications for genetic diseases, such as cancer and muscular dystrophy, that are sparked by missing proteins.

NIH New Innovator Award Won By M. D. Anderson Scientist For Innovative Research In Drug Resistance

A unique approach to understanding how cells develop resistance to drugs has won a scientist at The University of Texas M. D. Anderson Cancer Center a New Innovator Award from the National Institutes of Health. Gábor Balázsi, Ph.D., assistant professor in M. D. Anderson’s Department of Systems Biology, will receive $1.5 million over five years under the highly competitive program.

C. Difficile Hypervirulence Genes Identified

Five genetic regions have been identified that are unique to the most virulent strain of Clostridium difficile (C. difficile), the hospital superbug. Researchers writing in BioMed Central’s open access journal Genome Biology studied the genome of the bacterium, looking for genes relating to motility, antibiotic resistance and toxicity.

Chao Center Donates Medications To Combat Multidrug-Resistant Tuberculosis

The Chao Center for Industrial Pharmacy & Contract Manufacturing officials announced that they will donate about 1,800 bottles of a medication to help fight multidrug-resistant tuberculosis (MDR-TB) to Cambodia and Ethiopia. The Chao Center, which is based in the Purdue Research Park, produces and manufactures drugs in smaller quantities that can’t be produced in a cost-effective way by larger pharmaceutical companies.

Positron Exhibits At The American Society Of Nuclear Cardiology Annual Conference To Promote Their Cardiac Optimized Pet Scanner

Positron Corporation (OTCBB:POSC) a molecular imaging solutions company focused on Nuclear Cardiology, will attend the 14th Annual American Society of Nuclear Cardiology (ASNC) annual conference in Minneapolis, Minnesota October 1-4, 2009 to showcase their newly developed cardiac optimized PET scanner, the Attrius™ (http://www.asnc.org).

Imager That Identifies, Locates Individual Cancer Cells, Built By Case Western Reserve University Scientist

Dave Wilson was dissatisfied with blurry, low-sensitivity optical images of diseased tissues. So, four years ago he set out to create a better imager. Now, Wilson, a professor of biomedical engineering at Case Western Reserve University, can identify a single cancer cell in preclinical imaging studies. And he can pinpoint exactly where the cell is located in a three-dimensional image.

Electronic Alerts About Abnormal Imaging Test Results Do Not Always Result In Timely Follow-Up

Abnormal results on outpatient imaging tests sometimes may not receive timely follow-up even when clinicians receive and read results in an advanced, integrated electronic medical record system, according to a report in the September 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Wayne State University To Lead First Ever Combined Imaging And Genetics Study In Childhood OCD

Wayne State University officials announced an expansion of a research grant of nearly $2.7 million, bringing the total award to over $6.1 million. This project, funded by the National Institute of Mental Health at the National Institutes of Health, is the first combined imaging and genetics research study on obsessive-compulsive disorder (OCD).

Positron Anticipates Cardiac PET Demand To Increase Due To Expanding Reimbursment Differential Between PET And SPECT Imaging

Positron Corporation (OTCBB:POSC) a molecular imaging solutions company focused on Nuclear Cardiology, predicts a significant rise in demand for Cardiac PET in 2010 with a proposed cut in SPECT reimbursement of 46% and an increase in PET reimbursement of 22%, issued by the Centers for Medicare & Medicaid Services (CMS).

Plaques Likely To Cause Heart Attacks Identified By Coronary Imaging Techniques

Late-breaking results from the PROSPECT clinical trial shed new light on the types of vulnerable plaque that are most likely to cause sudden, unexpected adverse cardiac events, and on the ability to identify them through imaging techniques before they occur.

How Can I Connect With My Autistic Child?

For fathers coming home from work and find it impossible to connect with their autistic child, it can typically be the straw that breaks the family’s back. Where most children will greet Daddy with a hug, many autistic children aren’t capable of affectionate interactions that keep a family intact. Emerson B.

Gender Difference In Elderly Suicide Risk After Previous Attempts

In older age groups, repeated suicide attempts constitute an increased risk for completed suicide in depressed women, while severe attempts constitute an increased risk for depressed men. Researchers writing in the open access journal BMC Psychiatry studied suicide attempts in 100 patients who committed suicide and in an age- and sex-matched control group, investigating the effects of age on suicidal behaviour, as a risk factor for accomplished suicide.

UNC Awarded $8.6 Million To Study Underlying Causes Of Psychiatric Disorders

Autism, depression, anxiety. Antipsychotic drug side effects. What are the genetic and environmental factors that underlie and contribute to these complex problems? And how do genes and environment interact to shape them? To seek answers, the National Human Genome Research Institute and the National Institute of Mental Health has named the University of North Carolina at Chapel Hill a Center of Excellence in Genomic Science and awarded UNC $8.

Two Problems, Many Solutions, Confederation Report Turns Spotlight On Dual Diagnosis – The NHS Confederation

NHS organisations need a mixture of improved training, greater awareness and partnership working to tackle the issues raised by patients with both a mental health condition and substance or alcohol misuse problems.

New Directory Features Sources Of Help For Psychiatric And Addiction Treatment

The National Association of Psychiatric Health Systems (NAPHS) has published a 2010 Membership Directory. The directory is a comprehensive referral resource providing information on the nation’s behavioral healthcare systems.

Hormone Therapy And Mammograms

Researchers from Boston University School of Medicine (BUSM) are recommending that menopausal women on hormone therapy (HT) continue their treatment prior to having their annual mammogram screenings. These recommendations appear as an editorial in the current on-line issue of Journal of the North American Menopause Society.

Religion Impacts Decision On Prostate Cancer Screening In African-American Men

African-American men are more likely to have had a digital rectal exam in the past year to screen for prostate cancer if they engage in religious behaviors, according to a University of Alabama at Birmingham (UAB) study published in the American Journal of Men’s Health. Study co-author Theresa A. Wynn, Ph.D.

How Living Conditions Impact Reproductive Health

When costs outweigh benefits, successful pregnancies are less likely to occur. Life is all about tradeoffs and recently published research by Virginia J. Vitzthum, a senior scientist at Indiana University’s Kinsey Institute for Research in Sex, Gender, and Reproduction, and professor in the IU College of Arts and Sciences’ Department of Anthropology, has shown that during periods of intense labor and low food intake, rates of early pregnancy loss can more than double.

National Survey: Health Care Providers Unlikely To Tell Men About Prostate Cancer Screening Risks

Health care providers are twice as likely to discuss the benefits rather than the risks associated with PSA (Prostate Specific Antigen) testing, despite national guidelines recommending full disclosure before screening, according to the results of national survey of men age 40 and older published in the September 28 issue of the Archives of Internal Medicine.